Stereoselective reduction of ketones by Daucus carota hairy root cultures

Abstract

Reduction of acetophenone by Daucus carota hairy root cultures afforded (S)-phenylethanol in high yield (96%) and excellent enantiomeric excess (ee  ≥ 98%). Aromatic ketones, keto esters, and a simple aliphatic ketone were reduced with good stereoselectivity (ee  = 62–98%) and moderate to high chemical yields (25–90%).

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